HDAC9 Antikörper

Produktnummer ABIN6568596

Der Kaninchen Polyklonal Anti-HDAC9-Antikörper wurde für WB validiert. Er ist geeignet, HDAC9 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für HDAC9 Antikörper (ABIN6568596)

Target: HDAC9 (Histone Deacetylase 9 (HDAC9))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HDAC9 Antikörper

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human HDAC9

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HDAC9

Target: HDAC9 (Histone Deacetylase 9 (HDAC9))

Andere Bezeichnung: Histone deacetylase 9

Hintergrund:

Synonyms: Histone deacetylase 9,HD9,Histone deacetylase 7B,HD7,HD7b,Histone deacetylase-related protein,MEF2-interacting transcription repressor MITR,HDAC9,HDAC7,HDAC7B,HDRP,KIAA0744,MITR

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.

Molekulargewicht:

Observed_MW: 97kDa

Calculated_MW: 57-65kDa/97-117kDa

Gen-ID: 9734

UniProt: Q9UKV0

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development